News digest – brain tumour awards, CAR T cell therapy, NHS ‘fast-tracking’ drugs and NICE decisions


Boosting brain tumour analysis

A yr on from the loss of life of Baroness Tessa Jowell, the previous Labour cupboard minister identified with glioblastoma who campaigned for funding and assist for brain tumours, three newly-funded brain tumour analysis groups have been assembled. Brain tumour survival has remained dismally low for years and our Brain Tumour Awards, in collaboration with The Brain Tumour Charity, will present £18 million to the three groups. The Occasions explored one in every of these groups’ targets of delivering potential new drugs to the brain utilizing nanotechnology.

For a whole have a look at what the groups have deliberate, try our weblog publish.

CAR T cell remedy on the NHS

The BBC spoke to Mike Simpson, who says his lymphoma is ‘on the run’ because of a brand new personalised immunotherapy therapy. CAR-T cell remedy trains the affected person’s personal immune cells to recognise and destroy most cancers cells. The therapy has been permitted on the NHS for sure blood cancers however, in accordance with Simpson – who turned one of many first NHS sufferers to obtain CAR T therapy after his most cancers got here again after chemo – the unwanted effects will be worse than chemotherapy.

NHS to ‘quick observe’ personalised most cancers medicines

Varied information shops, together with The Occasions and The Solar, are speaking about new “revolutionary” most cancers drugs. Simon Stevens, the top of NHS England, stated that he desires to ‘quick observe’ a selected new breed of personalised most cancers medicines often known as ‘tumour-agnostic’. The idea is that these drugs can goal any sort of most cancers so long as it carries a selected defective gene. However the gene fault in query is uncommon, and scientific trials have to date solely seen advantages in sufferers with uncommon most cancers varieties. So, what occurs subsequent? The drugs are awaiting evaluation by the Nationwide Institute of well being and Care Excellence (NICE) and nonetheless want a European licence, so there’s nonetheless a strategy to go earlier than they’re made accessible on the NHS.

Our weblog publish goals to supply some context to this week’s punchy headlines.

New therapy possibility on the NHS for some adults with leukaemia

In PharmaTimes this week, NICE permitted the drug blinatumomab (Blincyto), which means it is going to now be accessible on the NHS in England, Northern Eire and Wales for sufferers with a selected sort of leukaemia. Our information report has all the small print on how the drug works, and why NICE selected to reverse an preliminary rejection.

Most cancers not talked about sufficient in BAME communities

Bamidele Adenipekun, who was identified with breast most cancers in 2014, has been sharing her experiences with the BBC. She says that most cancers and different sicknesses are usually not talked about in some ethnic minority communities “as a consequence of concern”, which may result in ladies feeling “remoted”. Extra analysis is required to grasp why for some folks most cancers stays taboo.

NHS nonetheless laboured by outdated tech

It’s not a brand new story: the NHS can fall quick within the know-how division. A brand new survey requested IT-related well being sector employees about their experiences, and over one third stated that they’ve requested for sooner methods. Simply over a 3rd of these surveyed thought that NHS budgets had been holding again tech upgrades. PharmaTimes has the small print.

Girls’s alcohol consciousness and Scotland’s alcohol gross sales

Just one in 5 ladies surveyed at a number of breast clinics knew that ingesting alcohol will increase the danger of breast most cancers, in accordance with the BBC. Breast most cancers is the commonest sort of most cancers within the UK, with eight% of circumstances linked to alcohol. The researchers within the examine steered utilizing breast clinics and screening appointments as a chance to extend consciousness in regards to the hyperlink between alcohol and most cancers, however extra analysis is required to see whether or not it could really assist cut back most cancers threat.

In different alcohol associated information, gross sales have fallen to their lowest on document in Scotland, in accordance with the Mail On-line. However the price of deaths from alcohol-specific causes in each males and ladies has risen since 2012.

Preventing misinformation in science

Science isn’t any stranger to misinformation, however there could possibly be a strategy to fight it. Reported in a superb article by Vox, a examine discovered that when a press launch exaggerated outcomes, the information that covers that story would exaggerate too. The conclusion was potential technique to fight misinformation might begin with the Universities that put out the press releases.

And at last

A brand new examine, reported within the Telegraph, discovered that males who eat two or extra weekly servings of yoghurt could possibly be much less more likely to develop growths which may result in bowel most cancers than those that by no means eat yoghurt. However this examine wasn’t conclusive, and it’s troublesome to pinpoint the impact of 1 meals in our weight loss program. The issues we eat can have an effect on our intestine well being and the micro organism in our intestine, but it surely’s too early to say whether or not consuming extra yoghurt might cut back the danger of bowel most cancers.

Our weblog publish seems to be on the thrilling analysis that one in every of our groups is doing into the intestine microbiome.


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